Read this leaflet carefully before you start taking this medicine.  (DOWNLOAD)

• Keep this leaflet. You may need to read it again before, during or after use of this medicine. 
• If you have any further questions, ask your health care provider. • This medicine has been prescribed for you only. Do not pass it on to others. It  may harm them, even if their symptoms are the same as yours. 
• If any of the side effects become serious, or if you notice any side effects not  listed in this leaflet, please inform your health care provider. 

In this leaflet: 

1. What Tabufen Capsule is and what it is used for 
2. What you need to know before you take Tabufen Capsule 
3. How to use Tabufen Capsule 
4. Possible side effects 
5. How to store Tabufen Capsule 
6. Contents of the pack and other information 
7. WHAT TABUFEN CAPSULE IS AND WHAT IT IS USED FOR This medicine contains Ibuprofen which belongs to a group of medicines called  non-steroidal anti-inflammatory drugs (NSAIDs), which act to relieve pain and  reduce swelling. It can be used to relieve headaches, rheumatic and muscular  pain, pain from non-serious arthritic conditions, backache, migraine, period pain,  dental pain and neuralgia. It can also be used to reduce fever and relieve the  symptoms of colds and flu. 
8. WHAT YOU NEED TO KNOW BEFORE YOU TAKE TABUFEN CAPSULE This medicine can be taken by adults and children aged 12 years and over.  However, some people should not take this medicine or should seek the advice of  their pharmacist or doctor first. 

Do not take TABUFEN CAPSULE if: 

• Have a stomach ulcer, perforation, or bleeding, or have had one twice or more in  the past 
• Have had perforation or a bleeding stomach after taking a non-steroidal anti inflammatory medicine (you may have been sick and it contained blood or dark  particles that look like coffee grounds, passed blood in your stools or passed  black tarry stools) 
• Are allergic to ibuprofen or any other ingredients of the product, aspirin or other  non- steroidal anti-inflammatory medicines (you have ever had asthma, runny  nose, itchy skin or swelling of the lips, face or throat after taking these medicines) 
• Are taking aspirin with a daily dose above 75 mg, or other non-steroidal anti inflammatory medicines 
• Have severe heart, kidney or liver failure 
• Have an intolerance to some sugars, unless your doctor tells you to (this medicine  contains lactose) 
• Are pregnant, and in the last 3 months of pregnancy 

Warnings and precautions 

Talk to your doctor or pharmacist before taking Tabufen Capsules.  • Are elderly, as you may be more likely to suffer from side effects • Have or have had asthma, diabetes, high cholesterol, high blood pressure, a stroke, heart, liver, kidney or bowel problems 

• Are allergic to any other painkiller 
• Suffer from systemic lupus erythematosus (a chronic rheumatic disease) • Suffer from an allergy 
• Suffer from inflammation of the intestines (ulcerative colitis, Crohn’s disease) • Are on low-dose aspirin (up to 75 mg daily) 
• Are a smoker 
• Are in the first 6 months of pregnancy 
• If in adolescents this medicinal product is required for more than 3 days, or if  symptoms worsen a doctor should be consulted 
• Have an infection – please see heading “Infections” below. 

If you have heart problems, previous stroke or think you might be at risk of these  conditions (for example if you have high blood pressure, diabetes or high  cholesterol or are a smoker) you should discuss your treatment with your doctor  or pharmacist. 

Infections 

Tabufen Capsule may hide signs of infections such as fever and pain. It is 

therefore possible that Tabufen Capsule may delay appropriate treatment of  

infection, which may lead to an increased risk of complications. This has been  observed in pneumonia caused by bacteria and bacterial skin infections related to  chickenpox. If you take this medicine while you have an infection and your  symptoms of the infection persist or worsen, consult a doctor without delay. Other medicines and Tabufen Capsule 

Tell your doctor or pharmacist if you are taking, have recently taken or might take  any other medicines. 

Other medicines and Tabufen Capsules 

If you are taking any of the following medicines, please see your doctor  before taking the capsules: 

• Any other painkillers (aspirin or other NSAIDs). Do not take this medicine if you  are taking aspirin at doses of above 75mg daily. If you are on low-dose aspirin (up  to 75mg daily) speak to your doctor or pharmacist before you take Tabufen  Capsule. 
• Regular medication for high blood pressure (antihypertensives or diuretics) • Blood thinner medicines (anti-coagulants) 
• Corticosteroids (anti-inflammatory) which can increase the risk of side effects in  the stomach including bleeding 
• Anti-platelet agents (prevention of thrombotic cerebrovascular and cardiovascular  diseases) 
• Serotonine reuptake inhibitors and lithium (for treatment of depression – bipolar  disease and mania) 
• Cardiac glycosides (treatment of heart failure and cardiac arrhythmia) • Methotrexate (anti-cancer and psoriasis) 
• Zidovudine (HIV/AIDS infection) 
• Cyclosporine (prevent rejection after organ transplant) 
• Mifepristone (emergency contraceptive) 
• Tacrolimus (prevent rejection after organ transplant, treatment of skin diseases) • Quinolone (antibiotics) 

Some medicines that are anti-coagulants (i.e. thin blood/prevent clotting e.g.  aspirin/acetylsalicylic acid, warfarin, ticlopidine), some medicines that reduce high  blood pressure (ACE-inhibitors such as captopril, beta-blockers such as atenolol,  or angiotensin-II receptor antagonists such as losartan), and other medicines may  affect or be affected by treatment with ibuprofen. You should therefore always  seek advice of your doctor or pharmacist before you take ibuprofen with other  medicines. 

Pregnancy, breast-feeding and fertility 

If you are pregnant or breast-feeding, think you may be pregnant or are planning  to have a baby, ask your doctor or pharmacist for advice before taking this  medicine. 

Pregnancy and breast-feeding 

Ask your doctor or pharmacist before taking this medicine if you are in the first 6  months of pregnancy. DO NOT TAKE the capsules if you are in the last 3 months  of pregnancy. Ask your doctor or pharmacist for advice before taking any  medicine if you are breast-feeding. 

Fertility 

Tabufen Capsule belong to a group of medicines which may impair fertility in  women. This effect is reversible on stopping the medicine. It is unlikely that  Tabufen Capsule used occasionally, will affect your chances of becoming  pregnant, however, tell your doctor before taking this medicine if you have  problems becoming pregnant. 

Driving and using machines 

Tabufen Capsule are unlikely to cause any effect on your ability to drive or use  machines. 

3. HOW TO TAKE TABUFEN CAPSULES 

Use in children 

Not suitable for children under 12 years. 

For oral administration and short-term use only 

Dosage: Adults, the elderly, and children and adolescents over 12 years of age:  The minimum effective dose should be used for the shortest time necessary to  relieve symptoms. 1 or 2 capsules every 4-6 hours, as required. The capsules